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director@mrcindia.org

Bengaluru

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ICMR-NIMR Field Unit: Bengaluru, Karnataka

Bengaluru Field Unit was established in October 1992 mainly to demonstrate bioenvironmental malaria control strategy in Karnataka using different approaches in different eco-epidemiological settings and facilitate basic, operational and applied research activities of NIMR. In early 90s, malaria was a major public health problem in most parts of the state and the states’ contribution ranged from 7-10% of the total malaria cases reported in the country. The main mandate of the field unit is to demonstrate and suggest a suitable and appropriate malaria control strategy in different eco-epidemiological settings, to conduct basic, applied and operational research on malaria ; to provide technical support and capacity building of the State Health department staff in entomology and epidemiology; to evaluate new insecticides -indoor residual sprays and larvicides; efficacy testing of new intervention tools such as ITNs, ITCs and LLINs; efficacy testing of new drugs, diagnostic kits and new methods for diagnosis and treatment of malaria and to provide technical support to local health department in vector borne diseases control.

With the help of State Health Department, ICMR-NIMRFU successfully demonstrated bioenvironmental control of malaria in Tumkur, Kolar, Hassan, Chikmagalur, Mandya, Mysore, Kalaburgi, Raichur, Gadag, Yadgir, Mangalore, Chitradurga, Viajayapura, Bagalkot, etc. Many insecticide and LLIN trials were undertaken in different parts of the state. Stratification of Karanataka based on sibling species prevalence, vector distribution of Anopheles culicifacies and An. fluviatilis was undertaken. Now in many districts, malaria situation is under control. Apart from vector control activities, ICMR-NIMRFU also undertook evaluation of new drugs, diagnostic kits, clinical trials of antimalarials, etc.

Research Staff

Research Staff

  1. Alex Eapen, Scientist E & OIC (Additional Charge)
  2. Vani H C, Scientist D
  3. Sanal Kumar M, Technical Assistant
  4. MK Jaiswal, Lab Technician
  5. AN Verma, Lab Technician
  6. Renuka S, ICMR- Research Associate
Recent Research Publications

Recent Research Publications (last 5 years)

  1. Sreehari U, Raghavendra K, Tiwari SN, Sandhya S, Ghosh SK, Valecha N. Village scale (Phase III) evaluation of the efficacy and residual activity of SumiShield 50% WG (Clothianidin 50%) for indoor spraying for the control of pyrethroid resistant Anopheles culicifacies Giles in Karnataka state, India. Trop Med Int Health 2018;23(6):605-15.
  2. Sreehari U, Raghavendra K, Tiwari SN, Ghosh SK, Valecha N. Field testing and evaluation of the efficacy and duration of effectiveness of a biolarvicide, Bactivec® SC (Bacillus thuringiensis var. israelensis SH-14), in Bengaluru, India. Indian J Med Res 2018; 147 (3): 299-307
  3. Sreehari U, Raghavendra K, Tiwari SN, Sandhya S, Ghosh SK, Valecha N. Small scale (Phase II) evaluation of the efficacy and residual activity of SumiShield 50% WG (Clothianidin 50%) indoor spraying in comparison to deltamethrin, bendiocarb and pirimiphos methyl for malaria vector control in Karnataka state, India. J Vector Borne Dis 2018; 55: 122-9.
  4. Devaiah MK, Pradeep AS, Sowmya KB, Ghosh SK, Varadharajan S, Sreehari U, Tiwari SN, Anvikar AR, Valecha N. Midgut microbiota of Anopheles stephensi field derived strains and their influence on mosquitoes’ susceptibility to Plasmodium infections. Malar J 2018; 17:385.
  5. Sreehari U, Verma KM, Natarajan E, Velamuri PS, Raghavendra K. Adulticidal and larvicidal efficacy of three neonicotinoids against insecticide susceptible and resistant mosquito strains. Ind J Med Res. 142 (Suppl) 2015; 64-70.
  6. Tiwari SN, Ghosh SK, Sathyanarayan TS, Nanda N, Sreehari U, Valecha N. Malaria outbreaks in villages in North Karnataka, India, and role of sibling species of Anopheles culicifacies Complex. Health 2015; 7: 946-54.
  7. Uragayala S, Kamaraju R, Tiwari S, Ghosh SK, Valecha N.. Small-scale evaluation of the efficacy and residual activity of alpha-cypermethrin WG (250 g a.i./kg) spraying in comparison with alpha-cypermethrin WP (50 g a.i./kg) in India. Malar J 2015; 14:223
  8. Nagpal BN, Knox TB, Risintha P, Yadav RS, Ghosh SK, Sreehari U, Valecha N, Christophe E, Jamsheed M. Strengthening of vector control in South-East Asia: Outcomes from a WHO regional workshop. J Vector Borne Dis 2018; 55 (4) 247-257.
  9. Anvikar AR, Shah N, Dhariwal AC, Sonal GS, Pradhan MM, Ghosh SK, Valecha N. Epidemiology of Plasmodium vivax Malaria in India. Am J Trop Med Hyg 2016; 95 (6): 108-20.
  10. Verma KMV, Natarajan E, Velamuri PS, Sreehari U, Agrawal OP, Kamaraju R. Chlorfenapyr: Irritant effect compared to other insecticides and its intrinsic toxicity in multi-insecticide-susceptible and resistant Anopheles stephensi. J Vector Borne Dis 2015; 52(1):99-103.
  11. Elamathi N, Sreehari U, Raghavendra K. A note on new insights into vector control through in silico approaches. National Journal of Life Science (NJLS), 2015; 12 (3): 181-4.
  12. Dayanand KK, Punnath K, Chandrashekar V, Achur RN, Kakkilaya SB, Ghosh SK, Kumari S, Gowda DC. Malaria prevalence in Mangaluru city area in the southwestern coastal region of India. Malar J 2017; 16 (1): 492.
  13. Dykes CL, Das MK, Eapen A, Batra CP, Ghosh SK, Vijayan VA, Mishra S, Singh OP. Knockdown Resistance ( kdr ) Mutations in Indian Anopheles stephensi (Diptera: Culicidae) Populations. J Med Entomol 2016; 53 (2): 315-20.
  14. Joy S, Mukhi B, Ghosh SK, Achur RN, Gowda DC, Surolia N. Drug resistance genes: pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India. Malar J 2018; 17(1): 40.
  15. Ghosh SK. Molecular monitoring of antimalarial drug resistance in India. Indian J Med Microbiol. 2017; 35(2): 155.
  16. Dayanand KK, Punnath K, Chandrashekar VN, Kakkilaya SB, Ghosh SK, Tiwari SN, Achur RN, Kadambi SS, Gowda DC. Malaria transmission under an unusual circumstance causing death in two siblings. Am J Trop Med Hyg 2016; 95(1) 155-7.
  17. Ghosh Sk, Rahi M. Malaria elimination in India—The way forward. J Vector Borne Dis 2019; 56: 32-40
Ongoing Research Projects

Ongoing Research Projects

  1. Longitudinal community evaluation of survivorship, biological efficacy, fabric integrity and community acceptability of Miranet LN in comparison with Magnet LN as positive control in India.
  2. Longitudinal community evaluation of survivorship, biological efficacy, fabric integrity and community acceptability of Veeralin LN in comparison with Magnet LN as positive control in India.
  3. Longitudinal community evaluation of survivorship, biological efficacy, fabric integrity and community acceptability of Tsara Boost LN in comparison with Olyset Plus LN as positive control in India.
  4. Monitoring the efficacy of ACT for the treatment of uncomplicated Plasmodium falciparum malaria in India.
  5. Phase III evaluation of three formulations of Natular (20.6% EC, 2.5% G30 and 7.48% DT) against immatures of Aedes aegypti and Anopheles stephensi and two formulations (20.6% EC, 2.5% G30) against Culex quinquefasciatus in three ecoepidemiological settings in India

Address and contact details of Field Unit

ICMR- National Institute of Malaria Research Field Unit
First Floor, NirmalBhawan-ICMR Complex
Poojanahalli, Off NH-7 Airport Trumpet Bus Stop
Kannamangala Post, Devanahalli Taluk
Bengaluru-562110, Karnataka
Phone: +91 8105457528
E-mail: nimrbangalore@gmail.com

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